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Efficacy of a Marine Bacterial Nuclease against Biofilm Forming Microorganisms Isolated from Chronic Rhinosinusitis

BACKGROUND: The persistent colonization of paranasal sinus mucosa by microbial biofilms is a major factor in the pathogenesis of chronic rhinosinusitis (CRS). Control of microorganisms within biofilms is hampered by the presence of viscous extracellular polymers of host or microbial origin, includin...

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Hlavní autoři: Shields, Robert C., Mokhtar, Norehan, Ford, Michael, Hall, Michael J., Burgess, J. Grant, ElBadawey, Mohamed Reda, Jakubovics, Nicholas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575374/
https://ncbi.nlm.nih.gov/pubmed/23441151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055339
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