Mojo Hand, a TALEN design tool for genome editing applications

BACKGROUND: Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing. Effective design of TALENs requires a combination of selecting appropriate genetic features, finding pairs of binding sites based on a cons...

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Bibliographic Details
Main Authors: Neff, Kevin L, Argue, David P, Ma, Alvin C, Lee, Han B, Clark, Karl J, Ekker, Stephen C
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Software
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575288/
https://ncbi.nlm.nih.gov/pubmed/23323762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-1
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