In vivo evaluation of a conjugated poly(lactide-ethylene glycol) nanoparticle depot formulation for prolonged insulin delivery in the diabetic rabbit model

Poly(ethylene glycol) (PEG) and polylactic acid (PLA)-based copolymeric nanoparticles were synthesized and investigated as a carrier for prolonged delivery of insulin via the parenteral route. Insulin loading was simultaneously achieved with particle synthesis using a double emulsion solvent evapora...

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Autores principales: Tomar, Lomas, Tyagi, Charu, Kumar, Manoj, Kumar, Pradeep, Singh, Harpal, Choonara, Yahya E, Pillay, Viness
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575164/
https://ncbi.nlm.nih.gov/pubmed/23429428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S38011
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