Molecular Imaging of Inflammation and Platelet Adhesion in Advanced Atherosclerosis: Effects of Antioxidant Therapy with NADPH Oxidase Inhibition

BACKGROUND: In atherosclerosis, local generation of reactive oxygen species amplifies the inflammatory response and contributes to plaque vulnerability. We used molecular imaging to test whether inhibition of NADPH oxidase with apocynin would reduce endothelial inflammatory activation and endothelia...

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Detalhes bibliográficos
Main Authors: Liu, Ya Ni, Davidson, Brian P., Yue, Qi, Belcik, Todd, Xie, Aris, Inaba, Yoichi, McCarty, Owen J. T., Tormoen, Garth W., Zhao, Yan, Ruggeri, Zaverio M., Kaufmann, Beat A., Lindner, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575135/
https://ncbi.nlm.nih.gov/pubmed/23239832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.112.975193
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