Kinin B2 Receptor Mediates Induction of Cyclooxygenase-2 and Is Over-Expressed In Head and Neck Squamous Cell Carcinomas

Bradykinin (BK) has been shown to promote growth and migration of head and neck squamous cell carcinoma (HNSCC) cells via epidermal growth factor receptor (EGFR) transactivation. It has also been reported that BK can cause the induction of cyclooxygenase-2 (COX-2), a pro-tumorigenic enzyme, via the...

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Detalhes bibliográficos
Main Authors: Zhang, Weiping, Bhola, Neil, Kalyankrishna, Shailaja, Gooding, William, Hunt, Jennifer, Seethala, Raja, Grandis, Jennifer R., Siegfried, Jill M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575100/
https://ncbi.nlm.nih.gov/pubmed/19074839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-07-2197
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