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Immunoregulatory mechanisms and CD4-CD8- (double negative) T cell subpopulations in human cutaneous leishmaniasis: a balancing act between protection and pathology

Cellular immune responses directed against protozoan parasites are key for controlling pathogen replication and disease resolution. However, an uncontrolled, or improperly controlled, response can be deleterious to the host in terms of both allowing for the establishment of pathology, as well as les...

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Bibliographic Details
Main Authors: Gollob, Kenneth J., Antonelli, Lis R. V., Faria, Daniela R., Keesen, Tatjana S.L., Dutra, Walderez O.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575027/
https://ncbi.nlm.nih.gov/pubmed/18687296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2008.03.016
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