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FOR WHOM THE BELL TOLLS: DISTRESS SIGNALS FROM LONG-LIVED OSTEOCYTES AND THE PATHOGENESIS OF METABOLIC BONE DISEASES

Osteocytes are long-lived and far more numerous than the short-lived osteoblasts and osteoclasts. Immured within the lacunar-canalicular system and mineralized matrix, osteocytes are ideally located throughout bone to detect the need for, and accordingly choreograph, the bone regeneration process by...

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Detalhes bibliográficos
Main Authors: Manolagas, Stavros C., Parfitt, A. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574964/
https://ncbi.nlm.nih.gov/pubmed/23010104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2012.09.017
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