Cell-permeable probe for identification and imaging of sialidases

Alkyne-hinged 3-fluorosialyl fluoride (DFSA) containing an alkyne group was shown to be a mechanism-based target-specific irreversible inhibitor of sialidases. The ester-protected analog DFSA (PDFSA) is a membrane-permeable precursor of DFSA designed to be used in living cells, and it was shown to f...

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Detalhes bibliográficos
Main Authors: Tsai, Charng-Sheng, Yen, Hsin-Yung, Lin, Meng-I, Tsai, Tsung-I, Wang, Shi-Yun, Huang, Wen-I, Hsu, Tsui-Ling, Cheng, Yih-Shyun E., Fang, Jim-Min, Wong, Chi-Huey
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Physical Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574955/
https://ncbi.nlm.nih.gov/pubmed/23359711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222183110
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