HDAC3-selective inhibitor enhances extinction of cocaine-seeking behavior in a persistent manner

Nonspecific histone deacetylase (HDAC) inhibition has been shown to facilitate the extinction of drug-seeking behavior in a manner resistant to reinstatement. A key open question is which specific HDAC is involved in the extinction of drug-seeking behavior. Using the selective HDAC3 inhibitor RGFP96...

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Detalhes bibliográficos
Main Authors: Malvaez, Melissa, McQuown, Susan C., Rogge, George A., Astarabadi, Mariam, Jacques, Vincent, Carreiro, Samantha, Rusche, James R., Wood, Marcelo A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574934/
https://ncbi.nlm.nih.gov/pubmed/23297220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213364110
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