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Clustering of time-course gene expression profiles using normal mixture models with autoregressive random effects

BACKGROUND: Time-course gene expression data such as yeast cell cycle data may be periodically expressed. To cluster such data, currently used Fourier series approximations of periodic gene expressions have been found not to be sufficiently adequate to model the complexity of the time-course data, p...

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Detalhes bibliográficos
Main Authors: Wang, Kui, Ng, Shu Kay, McLachlan, Geoffrey J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574839/
https://ncbi.nlm.nih.gov/pubmed/23151154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-300
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