Glutamate Receptor 1 Phosphorylation at Serine 831 and 845 Modulates Seizure Susceptibility and Hippocampal Hyperexcitability after Early Life Seizures

Neonatal seizures can lead to later life epilepsy and neurobehavioral deficits, and there are no treatments to prevent these sequelae. We showed previously that hypoxia-induced seizures in a neonatal rat model induce rapid phosphorylation of serine-831 (S831) and Serine 845 (S845) sites of the AMPA...

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Bibliografiska uppgifter
Huvudupphovsmän: Rakhade, Sanjay N., Fitzgerald, Erin F., Klein, Peter M., Zhou, Chengwen, Sun, Hongyu, Huganir, Richard L., Jensen, Frances E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2012
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574823/
https://ncbi.nlm.nih.gov/pubmed/23223299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6121-11.2012
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