Tumor-Specific Expression of Organic Anion-Transporting Polypeptides: Transporters as Novel Targets for Cancer Therapy

Members of the organic anion transporter family (OATP) mediate the transmembrane uptake of clinical important drugs and hormones thereby affecting drug disposition and tissue penetration. Particularly OATP subfamily 1 is known to mediate the cellular uptake of anticancer drugs (e.g., methotrexate, d...

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Hlavní autoři: Buxhofer-Ausch, Veronika, Secky, Lena, Wlcek, Katrin, Svoboda, Martin, Kounnis, Valentinos, Briasoulis, Evangelos, Tzakos, Andreas G., Jaeger, Walter, Thalhammer, Theresia
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2013
Témata:
Review Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574750/
https://ncbi.nlm.nih.gov/pubmed/23431456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/863539
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