Tumor-Specific Expression of Organic Anion-Transporting Polypeptides: Transporters as Novel Targets for Cancer Therapy

Members of the organic anion transporter family (OATP) mediate the transmembrane uptake of clinical important drugs and hormones thereby affecting drug disposition and tissue penetration. Particularly OATP subfamily 1 is known to mediate the cellular uptake of anticancer drugs (e.g., methotrexate, d...

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Bibliografiske detaljer
Main Authors: Buxhofer-Ausch, Veronika, Secky, Lena, Wlcek, Katrin, Svoboda, Martin, Kounnis, Valentinos, Briasoulis, Evangelos, Tzakos, Andreas G., Jaeger, Walter, Thalhammer, Theresia
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2013
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574750/
https://ncbi.nlm.nih.gov/pubmed/23431456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/863539
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