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CD36-dependent signaling mediates fatty acid-induced gut release of secretin and cholecystokinin

Genetic variants in the fatty acid (FA) translocase FAT/CD36 associate with abnormal postprandial lipids and influence risk for the metabolic syndrome. CD36 is abundant on apical enterocyte membranes in the proximal small intestine, where it facilitates FA uptake and FA-initiated signaling. We explo...

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Hlavní autoři: Sundaresan, Sinju, Shahid, Rafiq, Riehl, Terrence E., Chandra, Rashmi, Nassir, Fatiha, Stenson, William F., Liddle, Rodger A., Abumrad, Nada A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574291/
https://ncbi.nlm.nih.gov/pubmed/23233532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-217703
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