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Molecular pathology of uveal melanoma

Like other cancers, uveal melanomas (UM) are characterised by an uncontrolled, clonal, cellular proliferation, occurring as a result of numerous genetic, and epigenetic aberrations. Signalling pathways known to be disrupted in UM include: (1) the retinoblastoma pathway, probably as a result of cycli...

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Podrobná bibliografie
Hlavní autoři: Coupland, S E, Lake, S L, Zeschnigk, M, Damato, B E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574255/
https://ncbi.nlm.nih.gov/pubmed/23222563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/eye.2012.255
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