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MAP Kinase-Mediated c-fos Regulation Relies on a Histone Acetylation Relay Switch

Gene activation is often associated with high levels of histone acetylation. Enhanced acetylation levels can promote the recruitment of further chromatin modifying complexes or the basal transcription machinery. Here, we have studied MAP kinase-mediated upregulation of c-fos and uncover a role for h...

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Detalhes bibliográficos
Main Authors: O'Donnell, Amanda, Yang, Shen-Hsi, Sharrocks, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574235/
https://ncbi.nlm.nih.gov/pubmed/18374651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.01.019
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