RhoA/Rho-Kinase and Nitric Oxide in Vascular Reactivity in Rats with Endotoxaemia

RhoA/Rho-kinase (RhoA/ROK) pathway promotes vasoconstriction by calcium sensitivity mechanism. LPS causes nitric oxide (NO) overproduction to induce vascular hyporeactivity. Thus, we tried to examine the role of RhoA/ROK and NO in the regulation of vascular reactivity in different time-point of endo...

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Bibliographic Details
Main Authors: Liao, Mei-Hui, Shih, Chih-Chin, Tsao, Cheng-Ming, Chen, Shiu-Jen, Wu, Chin-Chen
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574133/
https://ncbi.nlm.nih.gov/pubmed/23457552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056331
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