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Rapid Inverse Planning for Pressure-Driven Drug Infusions in the Brain

Infusing drugs directly into the brain is advantageous to oral or intravenous delivery for large molecules or drugs requiring high local concentrations with low off-target exposure. However, surgeons manually planning the cannula position for drug delivery in the brain face a challenging three-dimen...

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Hlavní autoři: Rosenbluth, Kathryn H., Martin, Alastair J., Mittermeyer, Stephan, Eschermann, Jan, Dickinson, Peter J., Bankiewicz, Krystof S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574124/
https://ncbi.nlm.nih.gov/pubmed/23457563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056397
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