Association of Plasminogen Activator Inhibitor-Type 1 (-675 4G/5G) Polymorphism with Pre-Eclampsia: Systematic Review

BACKGROUND AND AIMS: Excessive generation of plasminogen activator inhibitor-type 1 (PAI-1) is implicated in the pathogenesis of pre-eclampsia and related conditions. The PAI-1 (−675 4G/5G) promoter polymorphism (rs1799889) affects transcriptional activity and is a putative genetic risk factor for p...

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Bibliografiske detaljer
Main Authors: Morgan, Jessie A., Bombell, Sarah, McGuire, William
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574018/
https://ncbi.nlm.nih.gov/pubmed/23457639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056907
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