Development of a gene therapy strategy to target hepatocellular carcinoma based inhibition of protein phosphatase 2A using the α-fetoprotein promoter enhancer and pgk promoter: an in vitro and in vivo study

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Current therapies are insufficient, making HCC an intractable disease. Our previous studies confirmed that inhibition of protein phosphatase 2A (PP2A) may provide a promising therapeutic strat...

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Autors principals: Li, Wei, Li, Dao-Ming, Chen, Kai, Chen, Zheng, Zong, Yang, Yin, Hong, Xu, Ze-Kuan, Zhu, Yi, Gong, Fei-Ran, Tao, Min
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3574000/
https://ncbi.nlm.nih.gov/pubmed/23173703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-547
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