High yield derivation of enriched glutamatergic neurons from suspension-cultured mouse ESCs for neurotoxicology research

BACKGROUND: Recently, there has been a strong emphasis on identifying an in vitro model for neurotoxicity research that combines the biological relevance of primary neurons with the scalability, reproducibility and genetic tractability of continuous cell lines. Derived neurons should be homotypic, e...

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Bibliografiske detaljer
Main Authors: Hubbard, Kyle S, Gut, Ian M, Lyman, Megan E, Tuznik, Kaylie M, Mesngon, Mariano T, McNutt, Patrick M
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573964/
https://ncbi.nlm.nih.gov/pubmed/23095170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-127
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