Adenovirus-mediated delivery of interferon-γ gene inhibits the growth of nasopharyngeal carcinoma

BACKGROUND: Interferon-γ (IFN-γ) is regarded as a potent antitumor agent, but its clinical application is limited by its short half-life and significant side effects. In this paper, we tried to develop IFN-γ gene therapy by a replication defective adenovirus encoding the human IFN-γ (Ad-IFNγ), and e...

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Detalhes bibliográficos
Main Authors: Liu, Ran-yi, Zhu, Ying-hui, Zhou, Ling, Zhao, Peng, Li, Hong-li, Zhu, Lan-cai, Han, Hong-yu, Lin, Huan-xin, Kang, Liang, Wu, Jiang-xue, Huang, Wenlin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573957/
https://ncbi.nlm.nih.gov/pubmed/23272637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-256
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