Heparin-binding epidermal growth factor-like growth factor improves intestinal barrier function and reduces mortality in a murine model of peritonitis

BACKGROUND: The morbidity and mortality associated with bacterial peritonitis remain high. Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is a potent intestinal cytoprotective agent. The aim of this study was to evaluate the effect of HB-EGF in a model of murine peritoniti...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Yang, Jixin, Radulescu, Andrei, Chen, Chun-Liang, Zhang, Hong-Yi, James, Iyore O., Besner, Gail E.
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573883/
https://ncbi.nlm.nih.gov/pubmed/22703966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2012.04.002
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