In vitro and in vivo properties of a fully human IgG1 monoclonal antibody that combats multidrug resistant Pseudomonas aeruginosa

The development of an anti-bacterial drug in the form of a monoclonal antibody (mAb) targeting an exposed virulence factor, represents an innovative therapeutic strategy. Consequently, a fully human IgG1 mAb (LST-007) targeting Pseudomonas aeruginosa (PA) flagellin type b was recombinantly expressed...

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Main Authors: ADAWI, AZMI, BISIGNANO, CARLO, GENOVESE, TIZIANA, FILOCAMO, ANGELA, KHOURI-ASSI, CAMELLIA, NEVILLE, ANAT, FEUERSTEIN, GIORA Z., CUZZOCREA, SALVATORE, NEVILLE, LEWIS F.
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573743/
https://ncbi.nlm.nih.gov/pubmed/22735858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2012.1040
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