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HCO(3)(−)-independent conductance with a mutant Na(+)/HCO(3)(−) cotransporter (SLC4A4) in a case of proximal renal tubular acidosis with hypokalaemic paralysis

The renal electrogenic Na(+)/HCO(3)(−) cotransporter (NBCe1-A) contributes to the basolateral step of transepithelial HCO(3)(−) reabsorption in proximal tubule epithelia, contributing to the buffering of blood pH. Elsewhere in the body (e.g. muscle cells) NBCe1 variants contribute to, amongst other...

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Bibliografski detalji
Glavni autori: Parker, Mark D, Qin, Xue, Williamson, Rosalind C, Toye, Ashley M, Boron, Walter F
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573318/
https://ncbi.nlm.nih.gov/pubmed/22331414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.224733
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