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The phagocytic capacity and immunological potency of human dendritic cells is improved by α2,6‐sialic acid deficiency

Dendritic cells (DCs) play an essential role in immunity against bacteria by phagocytosis and by eliciting adaptive immune responses. Previously, we demonstrated that human monocyte‐derived DCs (MDDCs) express a high content of cell surface α2,6‐sialylated glycans. However, the relative role of thes...

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Detalhes bibliográficos
Main Authors: Cabral, M. Guadalupe, Silva, Zélia, Ligeiro, Dário, Seixas, Elsa, Crespo, Hélio, Carrascal, Mylène A., Silva, Mariana, Piteira, Ana R., Paixão, Paulo, Lau, Joseph T., Videira, Paula A.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573277/
https://ncbi.nlm.nih.gov/pubmed/23113614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12025
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