Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility

Peroxisomes are subcellular organelles involved in lipid metabolic processes, including those of very-long-chain fatty acids and branched-chain fatty acids, among others. Peroxisome matrix proteins are synthesized in the cytoplasm. Targeting signals (PTS or peroxisomal targeting signal) at the C-ter...

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Auteurs principaux: Mizuno, Yumi, Ninomiya, Yuichi, Nakachi, Yutaka, Iseki, Mioko, Iwasa, Hiroyasu, Akita, Masumi, Tsukui, Tohru, Shimozawa, Nobuyuki, Ito, Chizuru, Toshimori, Kiyotaka, Nishimukai, Megumi, Hara, Hiroshi, Maeba, Ryouta, Okazaki, Tomoki, Alodaib, Ali Nasser Ali, Amoudi, Mohammed Al, Jacob, Minnie, Alkuraya, Fowzan S., Horai, Yasushi, Watanabe, Mitsuhiro, Motegi, Hiromi, Wakana, Shigeharu, Noda, Tetsuo, Kurochkin, Igor V., Mizuno, Yosuke, Schönbach, Christian, Okazaki, Yasushi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
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Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573110/
https://ncbi.nlm.nih.gov/pubmed/23459139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003286
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