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Tysnd1 Deficiency in Mice Interferes with the Peroxisomal Localization of PTS2 Enzymes, Causing Lipid Metabolic Abnormalities and Male Infertility

Peroxisomes are subcellular organelles involved in lipid metabolic processes, including those of very-long-chain fatty acids and branched-chain fatty acids, among others. Peroxisome matrix proteins are synthesized in the cytoplasm. Targeting signals (PTS or peroxisomal targeting signal) at the C-ter...

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Main Authors: Mizuno, Yumi, Ninomiya, Yuichi, Nakachi, Yutaka, Iseki, Mioko, Iwasa, Hiroyasu, Akita, Masumi, Tsukui, Tohru, Shimozawa, Nobuyuki, Ito, Chizuru, Toshimori, Kiyotaka, Nishimukai, Megumi, Hara, Hiroshi, Maeba, Ryouta, Okazaki, Tomoki, Alodaib, Ali Nasser Ali, Amoudi, Mohammed Al, Jacob, Minnie, Alkuraya, Fowzan S., Horai, Yasushi, Watanabe, Mitsuhiro, Motegi, Hiromi, Wakana, Shigeharu, Noda, Tetsuo, Kurochkin, Igor V., Mizuno, Yosuke, Schönbach, Christian, Okazaki, Yasushi
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573110/
https://ncbi.nlm.nih.gov/pubmed/23459139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003286
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