Reduced Syncytin-1 Expression Levels in Placental Syndromes Correlates with Epigenetic Hypermethylation of the ERVW-1 Promoter Region

Terminal differentiation of villous cytotrophoblasts (CT) ends in formation of the multinucleated syncytiotrophoblast representing the fetal-maternal interface. Aberrations during this cell-fusion process are associated with Intrauterine Growth Restriction (IUGR), Preeclampsia (PE) and High Elevated...

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Main Authors: Ruebner, Matthias, Strissel, Pamela L., Ekici, Arif B., Stiegler, Elisabeth, Dammer, Ulf, Goecke, Tamme W., Faschingbauer, Florian, Fahlbusch, Fabian B., Beckmann, Matthias W., Strick, Reiner
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3573012/
https://ncbi.nlm.nih.gov/pubmed/23457515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056145
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