Bioactivity-Guided Identification and Cell Signaling Technology to Delineate the Lactate Dehydrogenase A Inhibition Effects of Spatholobus suberectus on Breast Cancer

Aerobic glycolysis is an important feature of cancer cells. In recent years, lactate dehydrogenase A (LDH-A) is emerging as a novel therapeutic target for cancer treatment. Seeking LDH-A inhibitors from natural resources has been paid much attention for drug discovery. Spatholobus suberectus (SS) is...

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Detalhes bibliográficos
Main Authors: Wang, Zhiyu, Wang, Dongmei, Han, Shouwei, Wang, Neng, Mo, Feizhi, Loo, Tjing Yung, Shen, Jiangang, Huang, Hui, Chen, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572989/
https://ncbi.nlm.nih.gov/pubmed/23457597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056631
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