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Extracellular Regulated Kinase 1/2 Signaling Is a Critical Regulator of Interleukin-1β-Mediated Astrocyte Tissue Inhibitor of Metalloproteinase-1 Expression

Astrocytes are essential for proper central nervous system (CNS) function and are intricately involved in neuroinflammation. Despite evidence that immune-activated astrocytes contribute to many CNS pathologies, little is known about the inflammatory pathways controlling gene expression. Our laborato...

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Detalhes bibliográficos
Main Authors: Fields, Jerel, Cisneros, Irma E., Borgmann, Kathleen, Ghorpade, Anuja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572966/
https://ncbi.nlm.nih.gov/pubmed/23457635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056891
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