Regulation of the Membrane Insertion and Conductance Activity of the Metamorphic Chloride Intracellular Channel Protein CLIC1 by Cholesterol

The Chloride Intracellular ion channel protein CLIC1 has the ability to spontaneously insert into lipid membranes from a soluble, globular state. The precise mechanism of how this occurs and what regulates this insertion is still largely unknown, although factors such as pH and redox environment are...

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Detalhes bibliográficos
Main Authors: Valenzuela, Stella M., Alkhamici, Heba, Brown, Louise J., Almond, Oscar C., Goodchild, Sophia C., Carne, Sonia, Curmi, Paul M. G., Holt, Stephen A., Cornell, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572944/
https://ncbi.nlm.nih.gov/pubmed/23457643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0056948
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