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Measuring in vivo tumor pHe with CEST-FISP MRI

PARACEST MRI contrast agents have been developed that can measure pH in solution studies, but these agents have not previously been detected in vivo. In order to use the PARACEST agent Yb-DO3A-oAA to measure the extracellular pH (pHe) in tumor tissue, a CEST-FISP MRI protocol was developed, the satu...

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Detalhes bibliográficos
Main Authors: Sheth, Vipul R., Li, Yuguo, Chen, Liu Qi, Howison, Christine M., Flask, Chris A., Pagel, Mark D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572795/
https://ncbi.nlm.nih.gov/pubmed/22028287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.23038
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