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The BEAF insulator regulates genes involved in cell polarity and neoplastic growth
Boundary Element Associated Factor-32 (BEAF-32) is an insulator protein predominantly found near gene promoters and thought to play a role in gene expression. We find that mutations in BEAF-32 are lethal, show loss of epithelial morphology in imaginal discs and cause neoplastic growth defects. To in...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572785/ https://ncbi.nlm.nih.gov/pubmed/22743648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.06.013 |
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