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The BEAF insulator regulates genes involved in cell polarity and neoplastic growth

Boundary Element Associated Factor-32 (BEAF-32) is an insulator protein predominantly found near gene promoters and thought to play a role in gene expression. We find that mutations in BEAF-32 are lethal, show loss of epithelial morphology in imaginal discs and cause neoplastic growth defects. To in...

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Detalhes bibliográficos
Main Authors: Gurudatta, B.V., Ramos, Edward, Corces, Victor G
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572785/
https://ncbi.nlm.nih.gov/pubmed/22743648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.06.013
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