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Generation of a Uracil Auxotroph Strain of the Probiotic Yeast Saccharomyces boulardii as a Host for the Recombinant Protein Production

BACKGROUND: Saccharomyces boulardii (S. boulardii) is the best known probiotic yeast. The genetic engineering of this probiotic strain requires the availability of appropriate mutants to accept various gene constructs carrying different selection markers. As the auxotrophy selection markers are unde...

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Autori principali: Hamedi, Hassan, Misaghi, Ali, Modarressi, Mohammad Hossein, Salehi, Taghi Zahraei, Khorasanizadeh, Dorsa, Khalaj, Vahid
Natura: Artigo
Lingua:Inglês
Pubblicazione: Avicenna Research Institute 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572704/
https://ncbi.nlm.nih.gov/pubmed/23626874
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