RORC2 Gene Silencing in Human Th17 Cells by siRNA: Design and Evaluation of Highly Efficient siRNA

BACKGROUND: RNA interference-based gene silencing has recently been applied as an efficient tool for functional gene analysis. RORC2 is the key transcription factor orchestrating Th17 cells differentiation, the cells that are known as the pathogenic elements in various autoimmune diseases. The aim o...

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Bibliographic Details
Main Authors: Hakemi, Mazdak Ganjalikhani, Ghaedi, Kamran, Andalib, Alireza, Homayouni, Vida, Hosseini, Mohsen, Rezaei, Abbas
Format: Artigo
Language:Inglês
Published: Avicenna Research Institute 2013
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572701/
https://ncbi.nlm.nih.gov/pubmed/23626872
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