Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice

Striatal functions depend on the activity balance between the dopamine and glutamate neurotransmissions. Glutamate inputs activate cyclin-dependent kinase 5 (Cdk5), which inhibits postsynaptic dopamine signaling by phosphorylating DARPP-32 (dopamine- and cAMP-regulated phosphoprotein, 32 kDa) at Thr...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yamamura, Yukio, Morigaki, Ryoma, Kasahara, Jiro, Yokoyama, Hironori, Tanabe, Akie, Okita, Shinya, Koizumi, Hidetaka, Nagahiro, Shinji, Kaji, Ryuji, Goto, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572678/
https://ncbi.nlm.nih.gov/pubmed/23420105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00012
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados