Small molecule fluorophore and copolymer RGD peptide conjugates for ex vivo two-photon fluorescence tumor vasculature imaging

We report the use of small molecule and block copolymer RGD peptide conjugates for deep ex vivo imaging of tumor vasculature in “whole” excised tumors using two-photon fluorescence microscopy (2PFM). The fluorescent probes were administered to mice via tail-vein injection, after which the tumors wer...

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Autori principali: Morales, Alma R., Yanez, Ciceron O., Zhang, Yuanwei, Wang, Xuhua, Biswas, Sanchita, Urakami, Takeo, Komatsu, Masanobu, Belfield, Kevin D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572548/
https://ncbi.nlm.nih.gov/pubmed/22940216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.06.082
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