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Caspase 3 Cleavage of the Inositol 1,4,5-Trisphosphate Receptor Does Not Contribute to Apoptotic Calcium Release
An important role in the regulation of apoptotic calcium release is played by the ubiquitously expressed family of inositol 1,4,5-trisphosphate receptor (IP(3)R) channels. One model for IP(3)R activation during apoptosis is cleavage by the apoptotic protease caspase 3. Here we show that early elevat...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572306/ https://ncbi.nlm.nih.gov/pubmed/23122728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2012.10.002 |
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