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The effect of pregabalin on sensorimotor gating in ‘low’ gating humans and mice

Pregabalin, an anticonvulsant and anxiolytic compound that binds to α2-δ auxiliary subunit Types 1 and 2 of voltage-gated calcium channels, has been shown to reduce excitatory neurotransmission partially through modulation of glutamatergic signaling. Prepulse inhibition (PPI) of startle is an operat...

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Hlavní autoři: Acheson, Dean T., Stein, Murray B., Paulus, Martin P., Geyer, Mark A., Risbrough, Victoria B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572212/
https://ncbi.nlm.nih.gov/pubmed/22575075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2012.04.018
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