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A novel adenoviral vector labeled with superparamagnetic iron oxide nanoparticles for real-time tracking of viral delivery

In vivo tracking of gene therapy vectors challenges the investigation and improvement of biodistribution of these agents in the brain, a key feature for their targeting of infiltrative malignant gliomas. The glioma-targeting Ad5/3-cRGD gene therapy vector was covalently bound to super-paramagnetic i...

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Detalhes bibliográficos
Main Authors: Yun, Jonathan, Sonabend, Adam M., Ulasov, Ilya V., Kim, Dong-Hyun, Rozhkova, Elena A., Novosad, Valentyn, Dashnaw, Stephen, Brown, Truman, Canoll, Peter, Bruce, Jeffrey N., Lesniak, Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572211/
https://ncbi.nlm.nih.gov/pubmed/22516547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jocn.2011.12.016
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