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Controlled release of nitric oxide chemotherapy using a nano-sized biodegradable multi-arm polymer

Nitric oxide is a cell signaling molecule that can be a potent inducer of cell death in cancers at elevated concentrations. Nitric oxide molecules are short-lived in vivo; therefore, NO-donating prodrugs have been developed that can deliver NO to tissues at micromolar concentrations. However, NO is...

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Detalhes bibliográficos
Main Authors: Duan, Shaofeng, Cai, Shuang, Yang, Qiuhong, Forrest, M. Laird
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572206/
https://ncbi.nlm.nih.gov/pubmed/22281420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.026
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