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Controlled release of nitric oxide chemotherapy using a nano-sized biodegradable multi-arm polymer
Nitric oxide is a cell signaling molecule that can be a potent inducer of cell death in cancers at elevated concentrations. Nitric oxide molecules are short-lived in vivo; therefore, NO-donating prodrugs have been developed that can deliver NO to tissues at micromolar concentrations. However, NO is...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3572206/ https://ncbi.nlm.nih.gov/pubmed/22281420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.01.026 |
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