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An Advanced Coarse-Grained Nucleosome Core Particle Model for Computer Simulations of Nucleosome-Nucleosome Interactions under Varying Ionic Conditions

In the eukaryotic cell nucleus, DNA exists as chromatin, a compact but dynamic complex with histone proteins. The first level of DNA organization is the linear array of nucleosome core particles (NCPs). The NCP is a well-defined complex of 147 bp DNA with an octamer of histones. Interactions between...

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Detalles Bibliográficos
Main Authors: Fan, Yanping, Korolev, Nikolay, Lyubartsev, Alexander P., Nordenskiöld, Lars
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3572162/
https://ncbi.nlm.nih.gov/pubmed/23418426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054228
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