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Safety and efficacy of high-dose daptomycin as salvage therapy for severe gram-positive bacterial sepsis in hospitalized adult patients

BACKGROUND: Increasing the dosage of daptomycin may be advantageous in severe infection by enhancing bactericidal activity and pharmacodynamics. However, clinical data on using daptomycin at doses above 6 mg/kg in Asian population are limited. METHODS: A retrospective observational cohort study of a...

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Detalhes bibliográficos
Main Authors: Lai, Chung-Chih, Sheng, Wang-Huei, Wang, Jann-Tay, Cheng, Aristine, Chuang, Yu-Chung, Chen, Yee-Chun, Chang, Shan-Chwen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571896/
https://ncbi.nlm.nih.gov/pubmed/23379510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-66
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