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Interleukin-10 Released by CD4(+)CD25(+) Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice
OBJECTIVE: We previously demonstrated that a reduced number of CD(4)(+)CD(25)(+)-regulatory T cells (Tregs) was associated with microvascular dysfunction in hypertension. However, the underlying mechanism by which Tregs regulate vascular endothelial function remains unknown. METHODS AND RESULTS: Con...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3571694/ https://ncbi.nlm.nih.gov/pubmed/21817097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.233262 |
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