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Interleukin-10 Released by CD4(+)CD25(+) Natural Regulatory T Cells Improves Microvascular Endothelial Function Through Inhibition of NADPH Oxidase Activity in Hypertensive Mice

OBJECTIVE: We previously demonstrated that a reduced number of CD(4)(+)CD(25)(+)-regulatory T cells (Tregs) was associated with microvascular dysfunction in hypertension. However, the underlying mechanism by which Tregs regulate vascular endothelial function remains unknown. METHODS AND RESULTS: Con...

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Detalhes bibliográficos
Main Authors: Kassan, Modar, Galan, Maria, Partyka, Megan, Trebak, Mohamed, Matrougui, Khalid
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571694/
https://ncbi.nlm.nih.gov/pubmed/21817097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.233262
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