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The Kaposi's Sarcoma-Associated Herpesvirus ORF34 Protein Binds to HIF-1α and Causes Its Degradation via the Proteasome Pathway

Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent for Kaposi's sarcoma (KS) and two other lymphoproliferative disorders, primary effusion lymphoma (PEL) and multicentric Castleman's disease (MCD). Kaposi's sarcoma is a highly vascular tumor, and recently both...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Haque, Muzammel, Kousoulas, Konstantin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571462/
https://ncbi.nlm.nih.gov/pubmed/23221556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02460-12
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