Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

The mammalian target of rapamycin (mTOR) downstream of phosphatidylinositol 3-kinase (PI3K) in the growth factor receptor (GFR) pathway is a crucial metabolic sensor that integrates growth factor signals in cells. We recently showed that human papillomavirus (HPV) type 16 exposure activates signalin...

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Bibliographic Details
Main Authors: Surviladze, Zurab, Sterk, Rosa T., DeHaro, Sergio A., Ozbun, Michelle A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571372/
https://ncbi.nlm.nih.gov/pubmed/23255786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02319-12
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