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Differential Replication of Pathogenic and Nonpathogenic Strains of West Nile Virus within Astrocytes

The severity of West Nile virus (WNV) infection in immunocompetent animals is highly strain dependent, ranging from avirulent to highly neuropathogenic. Here, we investigate the nature of this strain-specific restriction by analyzing the replication of avirulent (WNV-MAD78) and highly virulent (WNV-...

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Autores principales: Hussmann, Katherine L., Samuel, Melanie A., Kim, Kwang S., Diamond, Michael S., Fredericksen, Brenda L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571364/
https://ncbi.nlm.nih.gov/pubmed/23269784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02577-12
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