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Trypanosoma brucei FKBP12 Differentially Controls Motility and Cytokinesis in Procyclic and Bloodstream Forms

FKBP12 proteins are able to inhibit TOR kinases or calcineurin phosphatases upon binding of rapamycin or FK506 drugs, respectively. The Trypanosoma brucei FKBP12 homologue (TbFKBP12) was found to be a cytoskeleton-associated protein with specific localization in the flagellar pocket area of the bloo...

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Detalhes bibliográficos
Main Authors: Brasseur, Anaïs, Rotureau, Brice, Vermeersch, Marjorie, Blisnick, Thierry, Salmon, Didier, Bastin, Philippe, Pays, Etienne, Vanhamme, Luc, Pérez-Morga, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571288/
https://ncbi.nlm.nih.gov/pubmed/23104568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00077-12
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