Challenge of Chronically Infected Mice with Homologous Trypanosoma cruzi Parasites Enhances the Immune Response but Does Not Modify Cardiopathy: Implications for the Design of a Therapeutic Vaccine

Chagas disease is a Trypanosoma cruzi-induced zoonosis that has no natural cure. Local damage induced by the parasite and the immune response causes chronic heart and digestive lesions. Efforts to develop a therapeutic vaccine that boosts the immune response to completely clear the parasite are need...

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Détails bibliographiques
Auteurs principaux: Rosas-Jorquera, Christian Emerson, Sardinha, Luiz Roberto, Pretel, Fernando Delgado, Bombeiro, André Luis, D'Império Lima, Maria Regina, Alvarez, José Maria
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2013
Sujets:
Clinical Immunology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571278/
https://ncbi.nlm.nih.gov/pubmed/23254299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00032-12
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